
How the TRAF1 arthritis mutation could reshape drug design
York University scientists have pinpointed a single change in the TRAF1 protein—at valine 196—that sharply dampens inflammatory signaling. The work, published in the Journal of Autoimmunity and reported by Drug Target Review, suggests a precision route for rheumatoid arthritis drugs. The study team, led by Associate Professor Ali Abdul-Sater, used gene editing to test how […]







